F.A.T Laboratories
Oral drugs are absorbed in finite time
The problem
According to the established view, drug absorption and elimination operate concurrently from zero time to infinity. This is unphysical and nonphysiological for the absorption process.
The solution
In reality, drug absorption and elimination operate concurrently from zero to F.A.T. (τ), while only elimination continues to operate until infinity. (Macheras P, Tsekouras AA. Columbus’ egg: Oral drugs are absorbed in finite
time. Eur J Pharm Sci. 2022 Sep 1;176:106265. doi:
10.1016/j.ejps.2022.106265. Epub 2022 Jul 19. PMID: 35863551. )